48 Results for "

Lonicera macrantha (D. Don) Spreng.

" in MedChemExpress (MCE) Product Catalog:
Products (48)

48 Results for "Lonicera macrantha (D. Don) Spreng." in MCE Product Catalog:

14
14 Cited Publications
Art. -Nr.: HY-108357
CAS. Nr.: 157-03-9
Reinheit:  99.98%
Synonyms: L-6-Diazo-5-oxonorleucine; DON
Forschungsgebiete:  

Infection Cancer

6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity .
9
9 Cited Publications
Art. -Nr.: HY-122218
CAS. Nr.: 1998725-11-3
Reinheit:  ≥98.0%
Target:  

Glutaminase

Forschungsgebiete:  

Neurological Disease

JHU-083, a proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b + cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals .
Art. -Nr.: HY-N11678
CAS. Nr.: 131180-21-7
Synonyms: DON-3-β-D-glucoside; Deoxynivalenol 3-glucoside
Target:  

Drug Metabolite

Deoxynivalenol-3-β-D-glucoside (DON-3-β-D-glucoside) is a plant metabolite of the Fusarium mycotoxin Deoxynivalenol (HY-N6684). Deoxynivalenol-3-β-D-glucoside exhibits lower toxicity than Deoxynivalenol in vitro and in vivo .
Art. -Nr.: HY-W099547
CAS. Nr.: 2197-63-9
Dihexadecyl hydrogen phosphateIt is an organic compound belonging to phospholipids. It's often used as an emulsifier, which means it helps mix two substances together that don't usually mix well, such as oil and water. Dihexadecyl hydrogen phosphateIt has several applications in the food industry, especially in the production of processed foods where it improves texture and stability. Additionally, it has applications in the pharmaceutical industry where it can be used ain the generation of micelles, liposomes, and other types of artificial membranes.
Art. -Nr.: HY-P991023
CAS. Nr.: 2911590-72-0
Synonyms: 6MW3211

Target:  

CD47 PD-1/PD-L1

Forschungsgebiete:  

Cancer

Safimestomig (6MW3211) is an CD47/PD-L1-targeting bispecific antibody. Safimestomig blocks CD47-mediated 'don't eat me' signaling and selectively binds to CD47 on tumor cells. Safimestomig blocks PD-L1-mediated immune checkpoint signaling. Safimestomig can be used for the research of cancer .
Art. -Nr.: HY-128775
CAS. Nr.: 2079938-92-2
Reinheit:  99.88%
Target:  

Drug Derivative

Forschungsgebiete:  

Cancer

JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) proagent. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST .
Art. -Nr.: HY-D0854
CAS. Nr.: 3244-88-0
Synonyms: Acid Violet 19; Acid fuchsin sodium
Acid Red is a class of synthetic dyes commonly used in the textile, paper and ink industries. They are in the category of acid dyes, which means they are water soluble and have acidic properties. Acid Red dye produces bright, vibrant colors that don't fade easily, but are not as durable as some other dyes. They can be used to dye a wide variety of fibers including wool, silk and nylon, as well as paper and leather.
Art. -Nr.: HY-N3706
CAS. Nr.: 15297-92-4
Target:  

Fungal

Dehydro-α-lapachone can be isolated from the methanol extract of stems of Catalpa ovata G Don. Dehydro-α-lapachone inhibits mycelial growth of Botrytis cinerea with IC50 value 0.41 mg/L .
Art. -Nr.: HY-N6685
CAS. Nr.: 50722-38-8
Synonyms: 3-AcDON; 3-ADON
3-Acetyldeoxynivalenol (3-AcDON; 3ADON), a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative, is a brain-penetrant Fusarium mycotoxin. 3-Acetyldeoxynivalenol induces mRNA expression and production of inflammatory chemokine IL-8 in intestinal cells .
Art. -Nr.: HY-108357R
CAS. Nr.: 157-03-9
Synonyms: L-6-Diazo-5-oxonorleucine (Standard); DON (Standard)
6-Diazo-5-oxo-L-nor-Leucine (Standard) is the analytical standard of 6-Diazo-5-oxo-L-nor-Leucine. This product is intended for research and analytical applications. 6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity[1][2][3].
Art. -Nr.: HY-117396
CAS. Nr.: 26871-46-5
Isomahanimbine is a natural carbazole alkaloid found in Murraya koenigii (L.) Spreng .
Art. -Nr.: HY-N16034
CAS. Nr.: 96552-96-4
Synonyms: Momordica saponin II; MS II
MS 2 (Momordica saponin II) is a vaccine adjuvant found in the seeds of perennial Momordica cochinchinensis Spreng .
Art. -Nr.: HY-179120
CAS. Nr.: 3095661-21-2
Target:  

Myosin

Forschungsgebiete:  

Infection

ZJS178 is a novel inhibitor of myosin I. ZJS178 is a fungicide that has inhibitory activity against Fusarium graminearum and can reduce DON toxin synthesis. ZJS178 can be used for research on plant diseases such as wheat scab .
Art. -Nr.: HY-153151
CAS. Nr.: 1998724-98-3
Target:  

Drug Intermediate

Forschungsgebiete:  

Cancer

Fmoc-DON-Boc (Compound 8b) is an Fmoc-protected compound that can be used for the synthesis of proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357). DON is a glutamine antagonist .
Art. -Nr.: HY-178717
CAS. Nr.: 3057478-36-8
Target:  

Fungal

Forschungsgebiete:  

Infection

WML-01 is a fungicide with EC50s of 0.079, 0.72 and 2.02 μg/mL against F. graminearum, F. fujikuroi and S. sclerotiorum. WML-01 disrupts the cell membrane of F. graminearum and induces deposition of lipid droplets. WML-01 inhibits Deoxynivalenol (DON) (HY-N6684) biosynthesis with no cross-resistance and strongly suppresses ribosomal subunit assembly, impairing protein synthesis. WML-01 effectively controls the fusarium head blight (FHB) epidemic .
Art. -Nr.: HY-N3371
CAS. Nr.: 77949-42-9
Synonyms: (-)-Longikaurin E
Longikaurin E is a diterpenoids compound isolated from the leaves of Rabdosia ternifolia (D. Don) .
Art. -Nr.: HY-N3067
CAS. Nr.: 30315-04-9
Picrasin B acetate is a Diterpenoids product that can be isolated from the herbs of Picrasma quassioides (D. Don) Benn .
Art. -Nr.: HY-N2726
CAS. Nr.: 355143-38-3
6'-O-p-Hydroxybenzoylcatalposide is a Iridoids product that can be isolated from the leaves of Catalpa ovata G. Don. .
Art. -Nr.: HY-N1623
CAS. Nr.: 14103-09-4
1-Hydroxy-2,3,4,7-tetramethoxyxanthone is a metabolite of xanthone that can be found in Halenia elliptica D. Don .
Art. -Nr.: HY-N11484
CAS. Nr.: 164022-74-6
5,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside is a natural product that can be isolated from the root of Scutellaria repens Buch.-Ham. ex D. Don .